question about metastats

mothur bugs
1

Hi all,

I used metastats (v.1.31.0) command to determine whether there are any species that are differentially represented between groups, but I found that the results of Mohtur were very different form the results of metastats software. And I think the result of metastats software is right. I used the same input file. why?

reslut of Mothur:
Synergistaceae 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000
Ignavibacteriaceae 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000
Patulibacteraceae 0.000000 0.000000 0.000000 0.000030 0.000000 0.000023 0.256574 0.180353

result of Metastats
Synergistaceae 0 0 0 0 0 0 1 1
Ignavibacteriaceae 0 0 0 0 0 0 1 1
Patulibacteraceae 0 0 0 2.27742647831099e-05 1.3263397374857e-09 1.82094737532809e-05 1 1

2

This will be fixed in our next release. For sparse OTUs mothur is outputting the permutted values instead of running the fisher exact test like metastats.