ParsScore

luxia · October 16, 2017, 5:28pm

Could someone explain the theory behind the ParsScore or give me a pointer on where to find more information about it? How do you tell if there is a significant difference in the clustering between two or more groups?

Cheers,
Luxia

PS. I am sorry if this has been asked before, i can not find a way to search this form (incl. google)

pschloss · October 20, 2017, 1:01pm

If you look at the TreeClimber paper, it describes the parismony method there.

ncbi.nlm.nih.gov

Introducing TreeClimber, a test to compare microbial community structures.

PD Schloss and J Handelsman, Applied and environmental microbiology, Apr 2006

The phylogenetic and ecological complexity of microbial communities necessitates the development of new methods to determine whether two or more communities have the same structure even though it is not possible to sample the communities exhaustively. To address this need, we adapted a method used in population genetics, the parsimony test, to determine the relatedness of communities. Here we describe our implementation of the parsimony test, TreeClimber, in which we reanalyzed six previously published studies and compared the results of the analysis to those obtained using integral-LIBSHUFF.

Pat

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ParsScore

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