Statistical analyses on UNIFRAC assigned distances

Theory behind mothur
1

Hi,

I calculated weighted and unweighted UNIFRAC distances from my sequences with the UniFrac command in mothur.
Now I would like to perform statistics on these distances. Normally, p values are calculated in the UniFrac command, however these p-values are, I think,
generated by comparing all sequences with each other (please correct me if I am wrong) and were not helpfull in my case (I would like to calculate differences between the clusters).
Could I use the AMOVA analyses in Mothur to calculate significant differences? Or do you have other suggestions?

Thank you for your help!
Giske

2

You can use unifrac, amova, homova, or anosim to compare these distances without a problem