non-sequence data

Hi mothur forum,
can I use dist.shared, pcoa and corr.axes with non-sequence data?
I modified my shared file. Numbers of sequences per OTUs were replaced with number of genes per COG.
I got PCoA and corr.axes results from it. I like to see how COGs make genomes differ and which COGs contribute the most to the differences. I know mothur better than R but unsure if commands are only for sequence data or if I can do this, i.e. results make sense?

Sure - shouldn’t be a problem.