Just a general question (I thought this was the best forum to post in).
What do you recommend for looking at 16S sequences parsed out of a shotgun metagenome? Since the sequences wont necessarily overlap they cant be aligned. Is there still a way to compare them to a pyrotag 16S library? Im thinking along the lines of a pCOA plot rather than a OTU analysis.
Anyways, any ideas would be much appreciated