I am trying to use Vsearch to cluster my denoised data, and I found the command “cluster” by using method=agc/dgc. Did anyone try this before? Can I continue the downstream analysis based on Vsearch results without .dist file?
Is there anyway i can use the .fasta and .count_table as input and run in Vsearch directly? I can’t find how to input .count_table in the Vsearch command.